Antibiotics

1) economize concisely slightly twain diametrical mechanisms by which antibiotic drugs work. It is possible for enzymes to involve themselves in the manufactu circumvent of the prison house cell besiege. If a cell wall fails to develop because the closing cross-linking reactions that make the cell wall rigid are non catalyzed, an antibiotic such as penicillin privy be used to encounter into the active localise of the enzyme that was to catalyze such a reaction. As the penicillin attaches, a covalent bond complex is formed that cannot be removed. Antibiotics can besides affect enzymes which catalyze metabolic reactions that can be found in bacterium. Sulfa drugs en adequate macrocosm to obtain the folic demigod coenzyme. Since they resemble PABA, they can be useful to the human aliment because PABA is what is converted to folic acid by bacteria development enzymes. While these enzymes catalyze metabolic reactions in bacteria, they do not alter human metaboli sm. 2) Write briefly about two different mechanisms by which some bacteria abide antibiotics. many bacteria possess a penicillinase enzyme that can clear the lactam ring (penicillin is a beta-lactam and contains a 4 membered beta-lactam ring). If the ring is opened the compound is ineffective and innocent to the bacteria. Some bacteria are resistant because they have conversions in their cell walls that do not allow entry to the antibiotic. 3) Write briefly about two different approaches scientists are attempt to combat antibiotic resistance Pharmacologists have tried to foster the beta-lactamase job by making penicillin derivatives that are able to withstand the hydrolytic enzyme In the example of patients with AIDS, the patient should take some(prenominal) types of drugs each for different enzymes reducing the risk that a miscellaneous will ascend and will be able to resist the drugs. If you want to bear a full essay, orde r it on our website: BestEssayCheap.com

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